Franz Diffusion Cell Apparatus Working. Diffusion cell apparatus 6 channel is the instrument meant for various test s like. Franz cell a versatile blown glass diffusion cell which locates the membrane horizontally and is usually used in the development of trans dermal products having a donor chamber open to the air and a stirred receptor chamber.
In general the franz diffusion cell is the current apparatus of choice from a regulatory perspective. The vertical franz diffusion cell is a simple reproducible test for measuring the in vitro drug release from creams ointments and gels. The test product is applied to the membrane via the top chamber donor compartment.
The test product is applied to the membrane via the top chamber donor compartment.
It is the de facto standard for working with human skin and may be used with any membrane 4mm or less in thickness. Franz diffusion cell transdermal permeation studies in vitro skin permeation in vitro skin permeation studies of topical formulationsthe vertical franz di. During topical drug product development ivrt may be used to profile the performance characteristics of several prototypes formulations as a screening tool. In general the franz diffusion cell is the current apparatus of choice from a regulatory perspective.
